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Enhancement pattern seen on MRI in PCNSL in immunocompetent patients and in PCNSL associated with acquired immunode ciency syndrome. In the latter, PCNSL lesions are often multiple and may appear cystlike or necrotic Johnson et al., 1997 ; . Although posttransplant systemic non-Hodgkin's lymphoma has been amply described, PT-PCNSL has been described in isolated case reports or as part of cohorts of posttransplant non-Hodgkin's lymphoma Barnett and Schwartz, 1974; Ciancio et al., 1997; Donnelly et al., 1998; Hardwidge et al., 1990; Krikorian et al., 1978; Kwan et al., 1992; Matas et al., 1976; Miller et al., 1997; Morrison et al., 1994; Murray et al., 1986; Penn and Starlz, 1972a, 1972b; Penn et al., 1969; Schneck and Penn, 1970, 1971; Schwechheimer et al., 1994; Tubman et al., 1983; van Diemen-Steenvoorde et al., 1986; Weintraub and Warnke, 1982 ; . Only 39 such cases have been published in the English language literature Table 1 ; , and most of these antedate modern neuro-imaging. Furthermore, no study has described serial neuro-imaging evaluations in these patients. Although the method of diagnosis of PCNSL and PT-PCNSL is usually stereotactic brain biopsy O'Neill et al., 1987 ; , previous reports have not commented on the potential complications of the procedure in this group of patients. Herein, we report the rst single-institution series with clinical, imaging, pathologic, and outcome data of patients with PT-PCNSL and summarize cases reported in the literature.

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Since 5 - 10% of participants did not provide drug data at the conclusion of allhat and these individuals are more likely to have deviated from randomised therapy, the rate of unconfounded continuation was probably as low as 50 - 60 and mesterolone.

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