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SYNOPSIS Lung cancer is the commonest cause of death from cancer in Australia. Almost all patients with small cell lung cancer are given chemotherapy either alone or in combination with radiotherapy. The use of chemotherapy in the management of metastatic non-small cell lung cancer has increased over the past decade. It can prolong survival and improve quality of life, when compared to best supportive care. Chemotherapy has an expanding role in the management of earlier stage disease and is now frequently included in combined modality treatment programs. Index words: antineoplastics, chemotherapy. Aust Prescr 2003; 26: 1035 ; Introduction Each year almost 7000 Australians die as a result of lung cancer, making this the commonest cause of death from cancer. Although efforts to reduce the proportion of the population who smoke have been successful in reducing the incidence of the disease in men, the number of new cases in women continues to rise. Up to 25% of patients present with early stage, localised disease that is amenable to surgical treatment. However, for the remainder, treatment often involves the use of chemotherapy, either as part of a potentially curative combination of therapies or as part of palliative therapy. There are two major types of lung cancer. These are small cell lung cancer and non-small cell lung cancer. Small cell lung cancer accounts for approximately 20% of all lung cancer and is a discrete histologic and clinical entity. Non-small cell lung cancer, which accounts for the remaining 80% of cases, is a term that encompasses several histologic types of tumour. These include adenocarcinoma also including bronchoalveolar carcinoma ; , squamous cell carcinoma and large cell carcinoma. As these tumours all behave in a similar way, their management is identical. Chemotherapy for non-small cell lung cancer Over the past decade there has been a marked increase in the use of chemotherapy. This has occurred as a consequence of two meta-analyses which showed that chemotherapy prolonged survival in metastatic disease1, 2, the availability of several new anticancer drugs3 and a recognition that combined modality treatment which includes chemotherapy produces better outcomes in patients with locally advanced disease. The newer drugs, which are associated with higher response rates and less toxicity than older drugs, include docetaxel, gemcitabine, paclitaxel and vinorelbine. However, none of these drugs was included in the meta-analyses. The newer drugs are usually used in combination with a platinum drug either cisplatin or carboplatin ; or, rarely, with one another. They may be used alone in less fit patients. Most people can be treated as outpatients. The usual administration schedules of these drugs, as well as common adverse effects, are summarised in Table 1. Febrile neutropenia is the most serious potential complication of chemotherapy for non-small cell lung cancer. This requires prompt assessment and management with broad-spectrum intravenous antibiotics. All of the newer drugs produce responses reduction of more than 50% in the cross-sectional area of tumours ; in 1525% of patients when they are used alone. Combinations which include cisplatin or carboplatin produce slightly higher response rates. Response rates are not good indicators of patient benefit. Therapeutic decisions should therefore not be based solely on response rates, but should take into account survival, control of symptoms, and quality of life. Metastatic non-small cell lung cancer Metastatic stage IV ; disease is incurable so the goals of treatment are to prolong life and palliate symptoms. Although early randomised trials failed to show a significant effect of chemotherapy on survival compared to best supportive care, Table 1 Drugs used in the treatment of small cell and non-small cell lung cancer Drug Usual duration and schedule for intravenous infusion.
Objectives. The purpose of this study was to examine the relationship of marijuana use to mortality. Methods. The study population comprised 65 171 Kaiser Permanente Medical Care Program enrollees, aged 15 through 49 years, who completed questionnaires about smoking habits, including marijuana use, between 1979 and 1985. Mortality follow-up was conducted through 1991. Results. Compared with nonuse or experimentation lifetime use six or fewer times ; , current marijuana use was not associated with a significandy increased risk of non-acquired immunodeficiency syndrome AIDS ; mortality in men relative risk [RR] 1.12, 12, 95 % confidence interval [C[] 0.89, 139 ; or of total mortality in women RR 1.09, 95% CI 0.80, 1.48 ; . Current marijuana use was associated with increased risk of AIDS mortality in men RR 1.90, 95% CI 133, 2.73 ; , an association that probably was not causal but most likely represented uncontrolled confounding by male homosexual behavior.'Ihis interpretation was supported by the lack of association of marijuana use with AIDS mortality in men from a Kaiser Permanente AIDS database. Relative risks for ever use of marijuana were similar. Conclusions. Marijuana use in a prepaid health care-based study cohort had little effect on non-AIDS mortality in and on total mortality in women. J Public Health. 1997; 87: 585-590, for example, cat dramamine.
CAP REDUCTION AS AN EEG MARKER OF HYPOAROUSABILITY IN NARCOLEPSY WITH CATAPLEXY Parrino L, Smerieri A, Del Felice A, Giglia F, Palomba V, Terzano MG Neuroscience, University, Parma, Italy Introduction : Narcolepsy is a sleep disorder with clinical symptoms attributed to a reduced activation of the arousal system. CAP cyclic alternating pattern ; is the expression of rhythmic arousability during NREM sleep. CAP parameters, arousals and conventional sleep measures, were studied in narcoleptic patients with cataplexy. Methods : Data were collected from all-night PSG recordings and the MSLT on the intervening day of 25 drug-naive patients 10 males and 15 females; mean age: 34 16 years ; after adaptation and exclusion of other sleep disorders. Clinical and neurological examination was integrated by laboratory blood chemistry with identification in all subjects of the HLA DQB1 * -0602, and by MSLT evaluation during the day with at least 2 SOREMPs. A group of 25 age- and gender-matched normal sleepers were selected as controls. Each PSG recording was subdivided into sleep cycles. Analysis of CAP included classification of A phases in subtypes A1, A2, A3. Results : There was an increase of the sleep period time mainly due to an increased wake time after sleep onset. REM latency was sharply reduced. The percentage of NREM sleep was slightly reduced and the balance between light sleep S1 + S2 ; and deep sleep S3 + S4 ; showed a curtailment of the former, while deep sleep was slightly increased. Excluding sleep cycles with SOREMPs, the duration of ordered sleep cycles was not different between narcoleptics and controls. The two groups showed similar values of arousal index, while CAP time, CAP rate, number of CAP cycles and of phase A subtypes in particular subtypes A1 ; were significantly lower in narcoleptic patients. Conclusion : The reduced periods of CAP in narcoleptic NREM sleep could be the EEG expression of a general hypoarousability that parallels the hypocretin orexin deficiency. This can explain some of the clinical correlates of the disorder, i.e., excessive sleepiness, short sleep latency and impaired attentive performances, without evidence of arousalinduced sleep fragmentation. The increased intrasleep wake time could be instead related to the enhanced percentage of REM sleep that shares common neurophysiological substrates with wakefulness. Support optional.
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John Pileggi started the feature with an outstanding run on Red, and pulled ahead of Dan in the third segment to take the win by four, with a new track record of 431. Rob had gone up a few thou, and was circulating, waiting for one of them to melt, but it was Todd who saw it all come apart in his second heat, and he finished 8th. Because, there was a B Main yet to run. Tom Gray, he of the lightning fast car, had been counseled by noted psychologist Todd Duda to seek retirement if he didn't take the overall win, and Tommy could still do this with a lap total higher than John's. Matched in the B Main with Tom and Stephen Jahl, and 9-year-old Henry Catfish, he had steady trackmates for his own assault on the record. But, after starting out with a 103 on the track's best lane, it was clear that Tommy's record run was just a cruel fantasy. In fact, Tom Jahl ran a truly superb race, and pulled past Tommy in the last heat to take the B Main win, and 4th overall, with a 387. Tommy was 5th with 386, Stephen Jahl, with a very impressive 380, was 6th, and Henry, with his best-ever finish in a MARC championship class event, was 7th. Many thanks to everyone for coming. Congratulations to all the folks who had best-ever finishes. We see real strides being made, and some hard work paying off. Our next date is November 23, on Jim and Kevin Macartney's oval. Bring the Dramamine.
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Table 4. Biochemical data mean SD ; in 54 GHD adults and 73 controls. Variable Total cholesterol mg dl ; HDL-chol mg dl ; LDL-chol mg dl ; Triglycerides mg dl ; Fasting glucose mg dl ; Fasting insulin U ml ; FIRI QUICKI Controls 227.340.0 53.513.5 143.338.2 GHD adults 238.847.8 39.28.7 164.748.8 P NS 0.01 0.05 0.001 and escitalopram, for example, dramamine album.
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Steal and 80% will steal under certain circumstances, if the opportunity arises. How can you protect your business from the 9 out of 10 employees that may be tempted to steal from your company? 1. Hire the right employees. Consider conducting background checks, especially for employees that handle inventory or money. 2. Since many employees that steal do so to support an addiction, it may be prudent to conduct random drug screenings. Remember to obtain written consent from the employees to ensure this information is gathered legally. 3. Let the employees know that youre watching. It may be wise to have security cameras monitor activity at cash registers as well as storage areas where inventory is kept. 4. Separate duties properly. Dont have one employee writing checks and reconciling bank statements. This gives too much control to that person. It provides not only an opportunity to steal from the company, but 6. 5.
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N October ground was broken in downtown Santa Barbara for a center for safe and supported housing, rehabilitation and socialization for people with mental illness and their families "This is the greatest milestone in our 58-year history, " proclaimed Mental Health Association in Santa Barbara County Board Chair George Kaufmann. "This is a giant step in telling the world that this is going to happen. Building Hope on Garden Street is now a reality." It began n 2001 when the Mental Health Association launched the Building Hope Capital Campaign, a community collaboration to build 51 units of much-needed, safe and affordable housing for individuals with mental illness and lowincome downtown workers at 617 Garden Street. The project serves as a model for private-public partnerships. Located at Cota and Garden Streets behind the Alano Club, the complex, which is expected to be completed in 2007, will also house the administrative office of the Mental Health Association and the Fellowship Club, its drop-in socialization and rehabilitation center that receives visits from more than 300 Club members each week. According to Tom Parker, President of the Hutton Foundation and co-chair of the capital campaign, one of the most exciting features of the mixed use community housing building is its financially self-sustaining design. Subsidized rents will fund ongoing mental health programs and esomeprazole.
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| Dramamine less drowsy for childrenIncreases in sexually transmitted diseases STDs ; among men who have sex with men MSM ; have coincided with recent increases in sexual risk behaviors across the United States and Europe. The identification of same-sex sexual risk behavior in men and the subsequent risk for certain bacterial and viral infections requires competency in taking a sexual history. Recent advances in the diagnosis and treatment of STDs have made STD management easier for physicians and patients and expanded the ability of a variety of health care professionals to participate in the management of STDs. This review focuses on recent developments in the epidemiology, pathogenesis, diagnosis, and management of common STDs in MSM and estrace.
Tablets of 5 mg each. Its competitor Buspidac-5 of Cadila-H costs only Rs 8.35 or Buspin of Intas at Rs 9.50. Triperidol Ethnor ; the only available brand of trifluperidol Hcl for acute and chronic psychosis has jumped up by 19 per cent. Zopicon of Intas, 7.5 mg zopiclone for insomnia has gone up by 19 per cent and remains the costliest. Anafranil of Novartis is clomipramine a drug for depression ; and the price has gone up by 14 per cent. Clonil Intas ; is also clomipramine and its price has increased by 19 per cent but still remains cheaper than Anafranil. Amineptine is a drug for depressive states and the only brand available is Survector of Serdia. Its price has shot up by 35 per cent. Likewise trimipramine, a drug for depression with associated sleep disturbances, and the only brand available is Surmontil of Rhone Poulenc has registered a price rise of 33 per cent for 10 mg and 46 per cent for 25 mg tablet. Among anti-emetics the only brand of dimenhydrinate Dramamiine Searle ; syrup has gone up by 44 per cent and injectible by 20 per cent. Stemetil of Rhone Poulenc is a popular brand of prochlorperazine, used for vertigo has increased by 11 per cent, and injectible by 16 per cent. Avomine Rhone Poulenc ; the only brand of promethazine widely used for nausea and motion sickness has gone up by 22 per cent. In the hypnotics, the most commonly used Gardenal for epilepsy ; has jumped up by 39 per cent and remains the costliest. Another anti-convulsant phenytoin sodium normally used for epilepsy and its popular brand Dilantin of Parke Davis has gone up by 21 per cent and Eptoin of Knoll, 50 mg tablet by 87.5 per cent and remains to be the costliest brand. Dilantin has become costliest at Rs 93.31 for 100 tablet of 100 mg, whereas the price of Epsolin of Cadila H costs Rs 44.75. Mysoline ICI ; , the only brand of primidone, used for epilepsy has gone up by 21 per cent. Metoclopromide is used for nausea, vomiting, gastritis, etc, and the two most popular brands are Maxeron of Wallace and Reglan of German Remedies. The price of Maxeron 10 mg tablet has gone up by 52 per cent, liquid by 51 per cent and injectible by 33 per cent. Reglan 10 mg by 34 per cent, syrup by 69 per cent and injectible by 51 per cent. But in spite of the rise, these are cheaper than Perinorm of Ipca. The price of Laxative PursenidIN of Novartis has gone up by 18 per cent and the anti-diarrhoeal Lomotil of Searle by 16 per cent. Uterine stimulant oxytocin is used for the induction of labour. The popular brand.
Field First Aid Kit: Gauze sponges 3x3 or 4x4 ; #30 Gauze bandage roll Cast padding Vetwrap 2 inch adhesive tape cloth ; Sterile pads such as Telfa Second Skin or New Kin for burns Triple antibiotic ointment Triple antibiotic ophthalmic ointment without hydrocorisone Betadine Rubbing alcohol or alcohol wipes Sterile saline for flushing wounds 60cc syringe for lavage or bulb syringe ; KY jelly Bandage scissors Tweezers or forceps Hemostats Wire cutters or leatherman tool has pliers, wire cutters, knife, etc. ; Ziploc bags, several sizes, and small garbage bags Latex gloves Thermal or heat packs Rectal thermometer Safety pins Triangular arm bandage cravat at least 3 Razor blade and 22g needle for splinters Nail clippers Space blanket SAM splint Antibiotics: Discuss this with your veterinarian and decide if it is appropriate useful for you to carry oral antibiotics in the field. Your vet can supply appropriate dosages. Also Carry in Your Vehicle or SAR Van: Greater quantities of all bandaging material Dog towels Old wash cloths for washing big areas Commercial ice packs like those used for sports injuries Splints Hydrogen peroxide to induce vomiting: 1 tblsp 10# every 5 minutes until dog vomits ; Kaopectate liquid Benadryl 25 mg 1-2 mg lb every 8 hrs for allergic reaction 4 mg lb for snakebite ; Buffered Aspirin 5 mg lb every 12 hrs ; on3 5 grain aspirin is approx. 325 mg. ; make sure it doesn't contain caffeine or other additives ; . Give with food. Drakamine 25-50 mg 1 hours before traveling try at home first Do NOT give tylenor or ibuprofen to any dog under any circumstances! You should carry your dogs regular diet in your field pack and vehicle and, or course, plenty of water. Always carry any medications your dog is on regularly and estradiol.
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Ackermann, E. 1970 ; . Biochem. Pharmac. 19, 1955. Daly, J. W. 1970 ; . Analyt. Biochem. 33, 286. Darby, F. J. 1971 ; . Biochem. J. 122, 41. Darby, F. J., Newnes, W. & Evans, D.A.P. 1970 ; . Biochem. Pharmac. 19, 1514. Kuntzman, R., Ikeda, M., Jacobson, M. & Conney, A. H. 1967 ; . J. Pharmac. exp. Ther. 157, 220. Tagg, J., Yasuda, D. M., Tanabe, M. & Mitoma, C. 1967 ; . Biochem. Pharmac. 16, 143. van Lier, J. E. & Kan, G. 1971 ; . Proc. Can. Fedn Biol. SOC8, 14, 367. van Lier, J. E. & Smith, L. L. 1970a ; . Biochim. biophy8. Acta, 210, 153. van Lier, J. E. & Smith, L. L. 1970b ; . Biochim. biophys. Acta, 218, 320. van Lier, J. E. & Smith, L. L. 1970c ; . Biochem. biophy8. Re8. Commun. 40, 3, because dramamind original.
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Kilimanjaro - Toiletry and medical items these are just a few suggestions and please bring these in small quantities to reduce the weight of your equipment. Toothbrush, toothpaste, feminine hygiene products Extra bootlaces Duct tape Wash kit with soap, toilet paper wipes Disinfectant wipes or Purell Minor first aid kit with o Antispetic o Bandages o Moleskin & other blister remedies o Anti-malarial pills, if applicable o Imodium, Pepto-Bismol o Dramamin4 if you tend to get car sick ; o Diamox, if applicable o Personal medications o Pain relievers, allergy medication o Insect repellant o Rehydration assistance or electrolyte replacement o Small scissors Kilimanjaro - Optional Items to Bring Sandals, flip-flops or lightweight sneakers for in camp Chocolate, candies, energy bars for quick energy en route Small camping pillow Gaiters Multi-tool or camp knife Lightweight book, journal or diary Waterproof backpack cover Safari Additional Items 2-3 short sleeve shirts; 1 extra pair shorts 2-3 long sleeve shirts for evenings and sun protection ; Additional or larger quantities of toiletry items Binoculars strongly recommend a good pair, not just small field binoculars ; Bigger heavier camera with zoon lens Sneakers, trail shoes or lighter weight hiking boots for game walks Northwest Voyageurs Provides Camping Tents and Mess Tent Sleeping pads Camp chairs Major First Aid kit All cooking equipment and meals and pseudoephedrine.
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References 6. 1. Current statistics from Cancer Research UK Kastner, P et al. 1990 ; . EMBO J 9: 1603-14 Rio, M.C. et al. 1987 ; PNAS 84: 9243-47 Enmark, E. and Gustafsson, J. 1999 ; J Internal Medicine 246: 133-38 REVIEW Green, S. et al. 1986 ; J. Steroid Biochemistry 24: 77-83 7. Jacquemier, J.D. et al. 1990 ; Breast Cancer Res Treatment 15: 109-17 Ponglikitmongkol, M. et al. 1988 ; EMBO J 7: 3385-88 Kuiper, G.G. et al. 1996 ; PNAS 93: 5925-30 Hanstein, B. et al. 2004 ; Eur J Endocrinol 150: 243-55 REVIEW 11. Tong, D. et al. 2002 ; Breast Cancer Res Treat. 71: 249-55 12. Chi, A. et al. 2003 ; Anticancer Research 23: 211-16 and finasteride and dramamine, for example, dramamine junior.
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H. Assay Contamination 1. 2. 3. The introduction of contaminating materials may occur if sufficient care is not taken during the assay procedure. TTUs must be decontaminated with buffered bleach as described in the Test Procedure. Do not reuse the TTUs. Perform regular decontamination of equipment and work surfaces as described above in Decontamination. As in any reagent system, excess powder on some gloves may cause contamination of opened tubes. It is recommended that operators use powderless gloves. 2. Low positive control values may be caused by incorrect temperatures during various steps in the assay or by allowing the selection time in the selection step to go longer than the recommended time. High backgrounds may occur if the selection time in the selection step is shortened, the selection temperature is not correct, or insufficient mixing occurs after the addition of the Selection Reagent. PSA analytes are tested in the same assay run ; , one analyte run may be invalid while the other analyte run is valid. The Exceptions Summary is found at the end of the Raw Run Report. For back-to-back runs where both analyte runs are valid, specimens listed in the Exceptions Summary may require retesting of one analyte. Although a PCA3 Score result may be listed in the Exceptions Summary, this result is not considered reportable until manual matching has been performed and the result is listed in a Ratio Report. If only one analyte was tested or if one analyte run is invalid, all specimens tested will be listed in the Exceptions Summary. Ratio Report The assay software automatically generates a Ratio Report for a back-to-back run where both analyte runs are valid. The software calculates and lists the PCA3 Score for the test specimens in the Ratio Report. Specimens listed in the Ratio Report either require no further testing or both analytes must be retested. Specimens not listed in the Ratio Report will be found in the Exceptions Summary section of the Raw Run Report. A Ratio Report can also be generated after manual matching see Manual Matching for more information ; . B. Matching 1. Automatic Matching In back-to-back runs where both analyte runs are valid, the software automatically matches the individual PCA3 and PSA analyte results for the test specimens and determines the PCA3 Score if calculable ; . The results are listed in the Ratio Report or Exceptions Summary of the Raw Run Report. 2. Manual Matching When PCA3 and PSA analytes are tested in different runs, the software cannot automatically determine the PCA3 Score. Manual matching of the analyte results is necessary to determine the PCA3 Score or PCA3 Score range refer to the PCA3 Assay Software Operator's Manual ; . Manual matching may also be required for results that are listed in the Exceptions Summary of the Raw Report. After manual matching, the PCA3 Score s ; for the matched specimen s ; will be listed in a new Ratio Report. C. Interpreting Reports 1. PCA3 Score Note: Only PCA3 Scores and PCA3 Score ranges listed in the Ratio Report are reportable. Results that appear in the Exceptions Summary may require further action and are not reportable. The PCA3 Score is calculated as the ratio of PCA3 mRNA copies to PSA mRNA copies, multiplied by 1000. Scores may only be calculated using results from valid runs and specimens. Invalid runs and invalid specimens must be retested for that analyte see Retesting for more information ; . If the reported PCA3 Score is below the cutoff, the result should be interpreted as NEGATIVE. If the PCA3 Score is above or equal to the cutoff, the result should be interpreted as POSITIVE. The laboratory director will establish the cutoff see Performance Characteristics for more information ; . Under some conditions, a PCA3 Score range [Calculated Score] or [Calculated Score] ; is provided. If [Calculated Score] is below the cutoff, the result should be interpreted as NEGATIVE. If [Calculated Score] is above the cutoff, the result should be interpreted as POSITIVE. If a numerical value is required, specimen dilution and retesting may generate a PCA3 Score instead of a PCA3 Score range see Retesting Dilution of Out-of-Range High Specimens.
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Differentiated being delirium, depression, concomitant physical illness, drug treatment, learning disability, the effects of a severely impoverished environment, and the normal memory loss that accompanies aging. Dementia is a clinical syndrome, and determining the cause of the syndrome is the second stage. The commonest cause is AD, followed by vascular dementia, Lewy-body dementia, and frontal lobe dementia. There are many so-called secondary causes of dementia, some of which are treatable. The clinical syndrome of dementia has three primary expressions. First, a neuropsychological element consisting of amnesia loss of memory aphasia either a receptive aphasia or expressive aphasia, the latter being more apparent in conversation, and nominal aphasia tested by direct questioning of naming of objects apraxia the inability to carry out tasks despite intact sensory and motor nervous systems, manifest in dementia most usually by an inability to dress often described as putting on a shirt or coat back and enalapril.
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1. , ., . , . 2002, 26. 2. Barrows, HS. Problem-based learning applied to medical education. Southern Illinois University School of Medicine, Springfield, Illinois. 2000 3. Mennin, S, et al. Faculty and student guide to problem-based learning tutorials in phase I curriculum of the Uni.
1, 1999 - 1 -adrenoceptors as targets for therapeutic agents in urology pre-congress satellite symposium, paris, july 23-24, 1998 in connection with the xiiith international congress of pharmacology, munich, july 26-31, 1998 guest editor: langer, bagneux pharmacology and pathology of the lower urinary tract benign prostatic hyperplasia bph ; signal transduction pathways associated with 1 -adrenoceptor subtypes in cells and tissues including human prostate marshall a , richard burt a , christopher chapple b a department of pharmacology, university college london, london; b department of urology, the royal hallamshire hospital, sheffield, uk address of corresponding author european urology 1999; -47 doi: 1 1159 000052317 ; key words signal transduction human prostate phospholipase c inositol 1, 4, 5-triphosphate ip 3 ; diacylglycerol protein kinase c 1a -adrenoceptors abstract the complexity of the signal transduction pathways linked to 1a -adrenoceptors are becoming clearer.
REFERENCES 1. Perspectives on the reporting of medical information. Address by Kenneth Shine. In: The Cantigny Conference Series: Ethical Issues in the Publication of Medical Information. Chicago, Ill: Robert R. McCormick Tribune Foundation; 1999: 161168. 2. Ransohoff DF, Ransohoff RM. Sensationalism in the media: when scientists and journalists may be complicit collaborators. Eff Clin Pract. 2001; 4: 185188. Angell M. Science on Trial. New York, NY: WW Norton & Co; 1996. 4. Hartz J, Chappell R. Worlds Apart: How the Distance Between Science and Journalism Threatens America's Future. Nashville, Tenn: First Amendment Center; 1997. 5. Shuchman M, Wilkes MS. Medical scientists and health news reporting: a case of miscommunication. Ann Intern Med. 1997; 126: 976-982. Shuchman M. Cancer treatment promising, if you're a mouse. Globe and Mail. April 4, 2000: R6. 7. Gottlieb M, Eichenwald K, Barbanel J. Health care's giant: powerhouse under scrutiny--a special report: biggest hospital operator attracts federal inquiries. New York Times. March 28, 1997: 1. Willman D. The new FDA: how a new policy led to seven deadly drugs. Los Angeles Times. December 20, 2000: 1. Nelson D, Weiss R. Gene test deaths not reported promptly. Washington Post. January 31, 2000: A1. 10. Whitaker R, Kong D, Globe staff. Doing harm: research on the mentally ill. Boston Globe. November 15, 1998: A1. 11. King RT. Bitter pill: how a drug firm paid for university study, then undermined it. Wall Street Journal. April 25, 1996: A1. 12. CBS News. 60 Minutes. Pharmaceutical industry power. Reported by Lesley Stahl; December 19, 1999.
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